
Chromasolv™ LC-MS Solvents
for PFAS Analysis
High-purity LC-MS solvents engineered to eliminate PFAS background noise — so your PFAS analytical workflows reflect your sample, not your solvent.
What is PFAS analysis?
Per- and polyfluoroalkyl substances (PFAS) are a broad class of thousands of chemically distinct compounds that vary widely in structure, environmental behavior, and properties. Some have been widely used in industrial processes and consumer products; some have been detected in water, soil, and biological samples.
Because PFAS encompasses such a diverse range of substances, accurate compound-specific analysis is essential. Laboratories, regulators, and researchers rely on PFAS analytical methods to identify which specific compounds are present, at what concentrations, and in what matrices. High-quality analytical data supports sound, science-based decision-making, whether for environmental monitoring, product stewardship, regulatory compliance, or research into the distinct characteristics of individual PFAS substances.
Chromasolv™ LC-MS solvents support PFAS detection across the full environmental cycle — from soil, surface water and groundwater through to consumer products.

•
Learn more about specific testing

PFAS testing in soil identifies which specific compounds are present, at what concentrations, and how they are distributed across a site. This data supports site characterization, regulatory compliance, and informed remediation planning. Because individual PFAS compounds differ in mobility, partitioning behavior, and environmental fate and transport, compound-specific soil analysis helps support that assessment and response decisions are grounded in the properties of the specific substances detected.

PFAS testing in water measures the concentrations of specific PFAS compounds in drinking water, groundwater, and surface water. Because individual compounds vary in solubility, transport behavior, and treatability, compound-specific water analysis provides the data needed to design effective treatment systems, evaluate compliance with applicable standards, and support long-term environmental monitoring. Accurate identification of which compounds are present, and at what levels, allows site managers and water systems to tailor their responses to the substances actually detected.

PFAS testing in consumer products identifies specific PFAS compounds in items such as food contact materials, cosmetics, packaging, cookware, textiles, and electronics. As product-level regulations increasingly specify limits for individual compounds or defined subsets of PFAS, manufacturers and retailers require compound-specific analytical data to verify compliance, substantiate marketing claims, and make informed formulation decisions. Accurate testing distinguishes between compounds that may be present as functional ingredients, processing residuals, or trace impurities, giving product stewards the granularity needed to respond to regulatory and market requirements with precision.
•
Why ultra-low background matters
Chromasolv™ high-purity solvents are engineered to remove these obstacles. Backed by more than a century of innovation legacy as Burdick & Jackson™ and Riedel-de Haën™, Chromasolv™ is manufactured under rigorous quality control to deliver the stability and ultra-low background noise that modern chromatography demands. Every lot undergoes stringent specification testing, to ensure uniform composition and reproducible results.
An ultra-low PFAS background in LC-MS solvents is particularly important for short-chain compound analysis, where regulatory reporting limits may approach the detection capabilities of the instrument itself. At those concentrations, solvent-derived signal can become indistinguishable from sample-derived signal, compromising data quality and potentially requiring costly retesting. Chromasolv solvents are evaluated to minimize this interference across a broad range of target analytes.
Using ultra-low PFAS LC-MS solvents is essential to maintain low background noise, achieve reliable detection at trace levels, and ensure the accuracy and credibility of PFAS analytical results.
•
Chromasolv™ LC-MS Solvents for PFAS Analysis
Available in the following bottles: 1L 45mm opening, 2.5L 45mm opening, and 4L sold by the case.
39290-4x2.5GL
39290-4x4L
39291-4x2.5GL
39291-4x4L
39292-4x2.5GL
39292-4x4L
Additional solvents, bottle sizes and packaging configurations may be available upon request.
Shop all ChromasolvChromasolv™ — Clear Separations, Pure and Simple
In chromatography, clarity is everything. Yet even trace impurities, baseline noise, or lot-to-lot variability in solvents can obscure peaks, compromise sensitivity, and introduce uncertainty into results. As analytical methods grow more sensitive and complex, particularly in HPLC, GC, and LC-MS workflows, scientists need solvents that perform consistently at the limits of detection. When solvent quality can’t keep pace with modern instrumentation, labs lose time and can’t trust their data.
Download BrochureCertificates of Analysis
Representative certificates for each Chromasolv™ LC-MS solvent for PFAS testing.
•