Medical Propellant
HFO-1234ze(E), GMP
As a near-zero global warming potential (GWP) propellant, our HFO-1234ze(E), GMP offers performance similar to HFC-134a and is a near drop-in replacement with only minimal changes required to equipment.
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Overview
HFO-1234ze(E), GMP is a breakthrough for pressurized metered dose inhalers (pMDIs). A non-flammable and low global warming potential (GWP) alternative to hydrofluorocarbons, it is non-ozone-depleting, VOC-exempt (U.S. EPA and CARB), with an ultra-low GWP of less than 1.
Specifications
General Information
- Application
- Propellant
- ASHRAE Number
- 34
- Chemical Name
- trans-1,3,3,3-Tetrafluoropropene
- Formula
- CF3-CH=CHF
- Linear Formula
- CF<sub>3</sub>CH=CHF
- Synonyms
- HFO-1234ze (E), 1234ze(E), trans-1234ze
Physical Properties
- Critical Density
- 489 kg/m3
- Critical Pressure
- 36.36 bar
- Expansion Ratio
- 247 at 1 atm and 60 °F (15.6 °C) (Liquid to Gas)
- Kauri-Butanol Value
- 12.5
- Liquid Density
- 1.17 g/mL at 21 °C
- Liquid Expansion Coefficient
- 0.0017 at 60 °F (15.6 °C)
- Liquid Viscosity
- 0.20 cP at 25 °C
- Molecular Weight
- 114 g/mol
- Solubility in Water
- 373 ppm at 20 °C
- Specific Gravity
- 3.958 at 60 °F (15.5 °C)
- Surface Tension
- 8.95 mN / m
- Vapor Pressure
- 3.4 bar (49 psig) at 21 °C
Temperature
- Boiling Point/Range
- -19 °C at 1 atm
- Critical Temperature
- 109.4 °C
Safety & Environment
- Flammable Range
- Non-Flammable (ASTM E-681/ISO 10156)
- Global Warming Potential
- <1
- Ozone Depletion Potential
- 0
Standards & Approvals
- ASHRAE Safety Classification
- A2L
General Information
- Application
- Propellant
- ASHRAE Number
- 34
- Chemical Name
- trans-1,3,3,3-Tetrafluoropropene
- Formula
- CF3-CH=CHF
- Linear Formula
- CF<sub>3</sub>CH=CHF
- Synonyms
- HFO-1234ze (E), 1234ze(E), trans-1234ze
Physical Properties
- Critical Density
- 489 kg/m3
- Critical Pressure
- 36.36 bar
- Expansion Ratio
- 247 at 1 atm and 60 °F (15.6 °C) (Liquid to Gas)
- Kauri-Butanol Value
- 12.5
- Liquid Density
- 1.17 g/mL at 21 °C
- Liquid Expansion Coefficient
- 0.0017 at 60 °F (15.6 °C)
- Liquid Viscosity
- 0.20 cP at 25 °C
- Molecular Weight
- 114 g/mol
- Solubility in Water
- 373 ppm at 20 °C
- Specific Gravity
- 3.958 at 60 °F (15.5 °C)
- Surface Tension
- 8.95 mN / m
- Vapor Pressure
- 3.4 bar (49 psig) at 21 °C
Temperature
- Boiling Point/Range
- -19 °C at 1 atm
- Critical Temperature
- 109.4 °C
Safety & Environment
- Flammable Range
- Non-Flammable (ASTM E-681/ISO 10156)
- Global Warming Potential
- <1
- Ozone Depletion Potential
- 0
Standards & Approvals
- ASHRAE Safety Classification
- A2L
- Formula : CF3-CH=CHF
- Linear Formula : CF3CH=CHF
- Chemical Name : trans-1,3,3,3-Tetrafluoropropene
- ASHRAE Number : 34
- Application : Propellant
- Synonyms : HFO-1234ze (E), 1234ze(E), trans-1234ze
- Liquid Expansion Coefficient : 0.0017 at 60 °F (15.6 °C)
- Solubility in Water : 373 ppm at 20 °C
- Kauri-Butanol Value : 12.5
- Critical Pressure : 36.36 bar
- Specific Gravity : 3.958 at 60 °F (15.5 °C)
- Molecular Weight : 114 g/mol
- Liquid Viscosity : 0.20 cP at 25 °C
- Critical Density : 489 kg/m3
- Surface Tension : 8.95 mN / m
- Expansion Ratio : 247 at 1 atm and 60 °F (15.6 °C) (Liquid to Gas)
- Vapor Pressure : 3.4 bar (49 psig) at 21 °C
- Liquid Density : 1.17 g/mL at 21 °C
- Critical Temperature : 109.4 °C
- Boiling Point/Range : -19 °C at 1 atm
- Ozone Depletion Potential : 0
- Global Warming Potential : <1
- Flammable Range : Non-Flammable (ASTM E-681/ISO 10156)
- ASHRAE Safety Classification : A2L
Sales Sheet
Name
Description
File Size
Date
Size
An Ultra-Low Global Warming Potential (GWP)
application/pdf 140.41 KB
5/4/2026
140.41 KB
An Ultra-Low Global Warming Potential (GEP) Medical Propellant for Metered Dose Inhalers
application/pdf 233.98 KB
5/4/2026
233.98 KB
Data Sheet
Name
Description
File Size
Date
Size
Technical Data Sheet
application/pdf 224.34 KB
5/22/2026
224.34 KB
Name
Description
File Size
Date
Size
An Ultra-Low Global Warming Potential (GWP)
application/pdf 140.41 KB
5/4/2026
140.41 KB
Technical Data Sheet
application/pdf 224.34 KB
5/22/2026
224.34 KB
An Ultra-Low Global Warming Potential (GEP) Medical Propellant for Metered Dose Inhalers
application/pdf 233.98 KB
5/4/2026
233.98 KB
Name
Description
File Size
Date
Size
An Ultra-Low Global Warming Potential (GEP) Medical Propellant for Metered Dose Inhalers
233.98 KB
5/4/2026
Technical Data Sheet
224.34 KB
5/22/2026
